Cleber Soares

Innovative Medication for Resistant Depression and Suicidal Ideation: HEOR Analysis From the Perspective of LMIC/Brazil/LATAM OBJECTIVES: In the context of real-world data on suicide numbers/ cases, we study the chance of a possible decrease in suicide ideation rates, based on scientific data and informations from a promising innovation (esketamine) clinical end point. METHODS: From database of the Notifiable Diseases Information System (SINAN) & Suicide data from the Mortality Information System (SIM) of the year 2022. A total of 496,583 cases of suicide from 2019 to 2022 in Brazilian scenario and a suicide attempt due to exogenous intoxication a subtotal of 4,259 cases, in one specific State (Pernambuco). Data from international literature showing esketamine intranasal and antidepressant treatment decreased: the risk of relapse by 51% (Hazard Ratio [HR], 0.49; 95% ci, 0.29-0.84) among patients who achieved stable remission, and 70% (HR, 0.30; 95% ci, 0.16-0.55) among those who achieved stable response compared to treatment with antidepressants and placebo. RESULTS: We speculate that 51% (Hazard Ratio [HR] of 496,583 CASES, means that esketamine and antidepressant treatment decreased the risk of relapse to avoidance risk of suicidal ideation in 253.257 cases. The 2,172 / 4,259 cases of attempted suicide reported in exogenous intoxication data, could contemplate the chances of rescue from “de novo" treatments and better clinical outcomes. CONCLUSIONS: For patients who have experienced remission or response after treatment with esketamine, there is a chance to resume a new treatment protocol in order to avoid loss of life or loss of productivity in cases of sequelae/suicide attempt. However, lengthy follow-up is needed in order to answer to this, with regard to economic impact and other outcomes.

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Last 25 of April MJV Technology & Innovation gathered the biggest health companies in Brazil for a brief discussion on #health and #technology. The event was named MJV Rethink Health. Here are some of the things technology is doing in this field, they are mind-blowing. Medical Imaging: AI algorithms are used to analyze medical images such as X-rays, MRIs, and CT scans to assist radiologists in diagnosing diseases like cancer, fractures, and abnormalities. AI can help in detecting patterns and anomalies that might be missed by human eyes, thus improving diagnostic accuracy and speed. Drug Discovery and Development: AI is used in pharmaceutical research to accelerate drug discovery and development processes. Machine learning algorithms can analyze vast amounts of biomedical data to identify potential drug candidates, predict their efficacy, and optimize clinical trial designs, ultimately reducing the time and cost involved in bringing new drugs to market. Personalized Medicine: AI algorithms can analyze individual patient data, including genetic information, medical history, and lifestyle factors, to tailor treatment plans and predict patient outcomes more accurately. Healthcare Administration: AI-powered tools are streamlining administrative tasks in healthcare facilities, such as patient scheduling, billing, and medical coding. Natural language processing (NLP) algorithms can automate documentation processes by converting spoken or written medical notes into structured data, reducing paperwork and administrative burdens on healthcare professionals. Telemedicine and Remote Monitoring: AI technologies are facilitating the expansion of telemedicine services and remote patient monitoring solutions. Virtual health assistants powered by AI can provide patients with personalized medical advice, reminders, and support, while wearable devices equipped with AI algorithms can continuously monitor vital signs and detect early signs of health deterioration. Predictive Analytics and Preventive Care: AI algorithms can analyze large datasets of patient health records to identify patterns and trends that may indicate potential health risks or outbreaks of diseases. By leveraging predictive analytics, healthcare providers can intervene proactively to prevent adverse health events and improve population health outcomes. Healthcare Robotics: AI-driven robots are being deployed in healthcare settings to assist with tasks such as medication delivery, patient monitoring, and surgical assistance. AI-powered clinical decision support systems (CDSS) are helping healthcare providers make evidence-based treatment decisions by integrating patient data, medical literature, and clinical guidelines. They can suggest diagnostic tests, recommend treatment options, and alert clinicians to potential drug interactions or adverse events, improving patient safety and quality of care. Pretty awesome :-) #ai

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This publication on the 1st Cleft Summit reflects the power of collaborative voices in fostering a unified approach for the management of complex issues & challenges facing the provider community globally. There is always power in unity.

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Data-driven decisions are key in the healthcare industry. Did you know the Brazilian market is projected to grow by 9.8% this year? This surge, coupled with a complex public-private healthcare system, presents a unique opportunity for pharmaceutical companies. In our latest article, written by Dr. Fisiologia on behalf of Pharma Meeting Brazil, we discuss more about all Brazil's advantages for foreign pharmaceutical companies. Download now to read the full article here: https://lnkd.in/dMwapyDv

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Read more (https://brnw.ch/21wJM1b) about how CAP Accreditation is demonstrable investment and supports ongoing educational, financial, and marketing objectives, including: - Preserving quality controls as Einstein laboratories scale-up - Educating laboratory managers and staff about new methodologies - Differentiating Einstein laboratories from the competition Integration of CAP accreditation supports growth, and by all measures, allowed Einstein to extend its benefits to thousands of more patients. While long recognized as the best hospital in Latin America, Forbes recently cited Einstein in their twenty “The Best Hospitals in the World” list and Newsweek ranked it 36th in its 2021“World Best Hospitals” survey.

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#CGM Diabetol Metab Syndr. 2023 Nov 25;15(1):242. doi: 10.1186/s13098-023-01208-5. Cost-effectiveness of continuous glucose monitoring with FreeStyle Libre® in Brazilian insulin-treated patients with types 1 and 2 diabetes mellitus Luciana Bahia 1, Karla F Mello 2, Lívia Lovato Pires Lemos 3, Naiane Lima Costa 3, Eduardo Mulinari 3, Domingos A Malerbi 2 Affiliations expand PMID: 38001509 PMCID: PMC10675900 DOI: 10.1186/s13098-023-01208-5 " a cost difference of R$ 7290, and an ICER of R$ 39,692.67 per QALY gained, in favour of CGM with FSL." #costeffectiveness for the win

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 🕒 EEGS Affiliate Webinar is coming in just one day! Don’t miss out your chance to learn for free the latest trends in the Affiliate Marketing Space and to be rewarded for it. 🎓 Register at the link below and join us tomorrow!   https://lnkd.in/dCxuNPRZ Andre Sousa Machado, MSc #EEGS #EEGSWebinar #Webinar #Affiliate #Marketing #MediaBuying

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Olá Brasileiros no Brasil e Brazilians worldwide! 🇺🇸🇧🇷 Calling all medical doctors and the pharmaceutical industry. In addition to new business executive programs, I've also created global communication programs for the specific needs of the medical and pharmaceutical industries. Currently, I am collaborating with 5 medical doctors focusing on their unique needs - domestically and globally. Check out my latest offerings: 👇 Interested? Have questions? Feel free to send me a private message. #globalcommunication #pharmaceuticalindustry #doctors

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We are pleased to share an insightful blog post on the "Operação Limpa Trilhos" initiative by the Receita Federal. This operation has led to a significant acceleration in the analysis of refund requests and compensation declarations. For further details, follow the link: https://ift.tt/xQbHdXC

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🔍 Unlocking Insights from Brazil’s Medical Device Landscape 🇧🇷 What’s New? We’ve seamlessly incorporated information directly from Brazil’s Health Regulatory Agency (Anvisa) into our platform. Now, you can explore comprehensive insights into the medical device landscape in Brazil. With 170,000+ medical devices and 30,000+ companies, our platform empowers you to make more informed decisions. 🚀 Why Brazil Matters? Brazil is a strategic hub for medical device companies. Understanding its regulatory pathway is crucial. NyquistAI simplifies this process by offering: - User-Friendly Interface: Say goodbye to language barriers and complex navigation. Our platform provides English translations and an intuitive interface. - Enhanced Access: Dive deep into Brazil’s medical device data, accelerating innovation and strategic decision-making. - Global Perspective: With Brazil onboard, our comprehensive view of the global medical device market continues to expand. Explore NyquistAI today and stay ahead in life sciences innovation. 💡🌟 www.nyquistai.com #LifeSciences #DataDrivenDecisions #MedicalDevices #nyquistai #regulatoryaffairs

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O marketing H2H - molecular e humano. in, Oliveira, Carlos Manuel - "Marketing pós-digital. O marketing à medida do ser humano", Outubro 2020, Actual/Almedina Editora e "Humantech Marketing. O marketing molecular e humano", Abril 2023, Actual/Almedina Editora. #marketing #humantechmarketing #estrategiademarketing #marketingonlife #marketingetecnologia #carlosmanueldeoliveira #marketingstrategy #marketingdigital #humantechmarketingroadtour #carlosmanueldeoliveira #digitalization #consumerbehaviour #marketingmania #GenAI #AI #marketingfuturo #futuremarketing #carlosmanueldeoliveira #marketingmania #branding #brandmanagement #brandmanagementnaeradigitalehumana #brandexperience #BrandEngagement #marketingposdigital #marketingh2h

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After having the opportunity to talk with several large organizations, it's clear that the future of corporate structure is changing, starting with the appointment of a CAIO or Chief AI Officer. Why is a CAIO position necessary? As AI revolutionizes the business world, CAIOs play a crucial role in efficiently guiding organizations through this transformation. This individual ensures that AI adoption is not just a technological upgrade, but a strategic change that permeates every aspect of the business. CAIOs bridge the gap between technological possibilities and business needs, aligning AI initiatives with overall organizational goals. This person will navigate the organization through complex AI contexts, manage associated risks, and foster a culture ready to embrace AI as a member of the organization. At its core, a CAIO is the architect of the organization's future, vital for maintaining competitiveness and driving innovation in the business world. As AI's role continues to grow, the main responsibilities of a CAIO include: 1. Defining AI vision and strategy 2. Coordinating AI use across the entire organization 3. Managing AI-related projects 4. Evaluating and selecting appropriate AI technologies 5. Managing risks and ethics in AI use 6. Developing AI skills among personnel 7. Communicating and building understanding about AI within the organization CAIOs help organizations use AI efficiently, create innovation, and increase competitiveness. Additionally, they help build an organizational culture ready to handle technological changes, enabling the organization to fully and sustainably benefit from AI in the long term.

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Tap to PIX? W-o-w. The president of the Brazil's Central Bank said yesterday he is working to enable that "soon". Just imagine the breakthrough in adoption. Also, regarding other upcoming PIX features, quoting him: 'For those recurring bills, such as Spotify and Netflix subscriptions, you'll soon be able to set them up on PIX Automático.' Intriguing, right? 😉 If you're a global company interested in accepting PIX, ensure you consult EBANX to make the most informed decision. https://lnkd.in/dDframR5

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workshop ECMO no doente Adulto

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Advantages of Bi-layer tablet ( double layer ) . it may compose several cases 1. Separates two incompatible actives to avoid stability problems 2. one layer IR immediate release the second layer CR or SR sustained release 3. one layer IR , second layer CR , Enteric coating 4. one layer IR second layer enteric granules , coating SR ,.... you can formulate further methods depending on your actives and their functionality ...

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