Explore the latest episode of Pharmaron's #DMPK Insights: “It’s ‘All-go’ with Oligos: Challenges and Opportunities in LC-MS of Therapeutics.” Join experts Robert MacNeill, Professor Michael Bartlett and Dr. Guilherme (Gui) Guimaraes as they delve into the dynamic world of oligonucleotide LC-MS. Discover the key challenges, the critical importance of sensitivity in these assays, and the innovative analytical approaches and technologies being developed and used today. Don't miss this insightful discussion & listen to the podcast: https://lnkd.in/dYUSmmkd Learn more about Pharmaron DMPK services, here: https://lnkd.in/dCGMgYjK #DMPKinsights #Pharmaron #Podcast #Oligos
关于我们
Pharmaron (Stock Code: 300759.SZ/3759.HK) is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and CGT products. With over 20,000 employees and operations in China, the U.S., and the U.K., Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China. Services: * Synthetic, medicinal and analytical chemistry services * Biology services * DMPK services * Pharmacology services * Drug safety assessment services * Radiochemistry and isotopically labelled metabolism services * Chemical & pharmaceutical development services * Clinical development services www.pharmaron.com CRO - Contract Research Organization & CDMO - Contract Development Manufacturing Organization Library Synthesis CADD Bioorganic Chemistry Discovery Process Chemistry Radiolabelled Chemical Synthesis ChemInformatics in vitro Biology in vitro Screening Structural Biology in vivo Pharmacology Animal Disease Models ex vivo Pharmacology Biomarkers in vitro ADME in vivo PK PKPD QA Regulatory Affairs Discovery Biologics Process Chemistry API Manufacturing Material Science Formulation Development Drug Product Manufacturing Toxicology Safety Pharmacology Genetic Toxicology DART Pathology Immunotoxicity Bioanalytical 14C / Carbon-14 Radiosynthesis 3H / Tritium Radiosynthesis QWBA mARG Clinical AME Mass Balance Metabolite Profiling Microdosing Phase 0 Absolute Bioavailability DDI First-in-Human (FIH) Thorough QT(TQT) Ethnobridging
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http://www.pharmaron.com
Pharmaron的外部链接
- 所属行业
- 制药业
- 规模
- 超过 10,001 人
- 总部
- Beijing
- 类型
- 私人持股
- 领域
- Chemistry、Biology、DMPK、Pharmacology、Chemical Development、Preclinical、Toxicology、Safety Pharmacology、Discovery、Lead Optimization、Process Development、Assay Development、ADME、Formulation、clinical pharmacology、analytical sciences、radiolabelled chemistry、accelerator mass spectrometry、radiolabelled compounds、API manufacturing、radiosynthesis、Biologics和CTG Products
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Pharmaron员工
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Advance Your Biologics and Cell & Gene Therapy with Pharmaron! From discovery to clinical development, Pharmaron offers comprehensive support for your biologics and CGT programs. Our expert team and cutting-edge facilities are here to bring our partner's innovations to life. • Biologics Laboratory Services: Seamless advancement from discovery to clinical development • Biologics CDMO: Extensive experience in developability assessment and more • Cell & Gene Therapy Laboratory Services: Robust support at all stages, from preclinical to clinical • Gene Therapy CDMO: cGMP biomanufacturing with advanced analytics Discover more about our full suite of services: https://lnkd.in/eQNq8udQ #Biologics #CellAndGeneTherapy #CGT #CDMO #CRO #Biotech #Pharma
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Still waiting for your cell lines to be made? Check out Pharmaron’s accelerated timelines for the generation of custom cell lines. Visit our website for more information: https://buff.ly/4cSuc8W #drugdiscovery #celllineengineering #celllinegeneration #cancerresearch #targetvalidation
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Discover how Pharmaron's analytical expertise can optimize your gene therapy development journey! Meet Angela Massey, Director of Analytical Sciences, who leads our efforts in: •Optimizing methods for minimal sample volumes •Enhancing endpoint testing with cutting-edge detection methods •Ensuring rigorous quality standards from start to finish Watch the video to learn how we can maximize your product testing efficiency while meeting critical quality attributes. Partner with Pharmaron for comprehensive analytical support in gene therapy. #GeneTherapy #AnalyticalDevelopment #AAV #Plasmid #Pharmaron #Innovation
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As part of our ongoing commitment to mental health and well-being, the mental health team at Pharmaron recently organized a fantastic activity that was met with great enthusiasm and engagement. 🌟 It was incredible to see so many colleagues come together, share their artistic talents, and enjoy a relaxing, collaborative experience. Activities like these not only help reduce stress, but also foster a sense of community and connection within our workplace. 🌟 A huge thank you to everyone who participated and made this event such a success. Your creativity and positive energy are truly inspiring! Learn more about our commitment to employee well-being here: https://lnkd.in/dmvX3p5q #Pharmaron #MentalHealth #Wellbeing #EmployeeEngagement
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Take advantage of the expertise of our team, who prioritizes quality and precision at every step, to achieve maximum success rates in creating the custom cell lines you need. Learn more about how Pharmaron's innovative cell line engineering services can meet any research objective and drive your projects forward by clicking here: https://lnkd.in/ebsNS5P3 #CellLineEngineering #DrugDiscovery #Biotechnology #Pharmaron #CRISPR
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Check out our colleague Robert MacNeill's latest #bioanalysis column on the nuanced, sometimes nuisance, nature of quantitative #lcms methodologies, particularly for complex modalities. Read here: https://lnkd.in/edFPDnQu Learn more about Pharmaron's comprehensive global small molecule bioanalysis capabilities, here: https://lnkd.in/e86aEcH6 #Pharmaron #drugdevelopment
It may lie at the heart of the #artofbioanalysis, so we all have some awareness of the importantly nuanced, sometimes nuisanced, nature of quantitative #lcms methodologies, particularly for complex modalities. Gloss over the fine details at your peril! #navigatethenuances with care and attention for #greatmethods ... #pharmaron #bioanalysis #HILICforthatHelix #tenyearsyammering https://lnkd.in/ep7jDUXf
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This week, we had the pleasure of hosting Prof. Ian Fairlamb from the University of York, as part of the Invited Speaker Programme. Prof. Fairlamb discussed how to improve outcomes of palladium-catalysed reactions for discovery and process chemistry. We thank Prof. Fairlamb for his visit! Learn more about Pharmaron’s process chemistry services: https://buff.ly/3UCRUjo #processchemistry #drugdiscovery #chemistry #drugdevelopment #pharmaron
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Join us for our next virtual chemistry lecture on Thursday, July 4, 2024, at 9:15 am (China Standard Time). 𝗦𝗲𝗹𝗲𝗰𝘁𝗶𝘃𝗲 𝗙𝘂𝗻𝗰𝘁𝗶𝗼𝗻𝗮𝗹𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗼𝗳 𝗣𝘆𝗿𝗶𝗱𝗶𝗻𝗲𝘀, 𝗗𝗶𝗮𝘇𝗶𝗻𝗲𝘀 𝗮𝗻𝗱 𝗣𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝗮𝗹𝘀 𝘃𝗶𝗮 𝗨𝗻𝗰𝗼𝗻𝘃𝗲𝗻𝘁𝗶𝗼𝗻𝗮𝗹 𝗜𝗻𝘁𝗲𝗿𝗺𝗲𝗱𝗶𝗮𝘁𝗲𝘀 Prof. Andy McNally Department of Chemistry Colorado State University Register for the webinar: https://lnkd.in/dKdJXAdc Pyridines and diazines are ubiquitous in pharmaceuticals and agrochemicals, yet there are limits in synthetic methods that can directly functionalize the C–H bonds in these structures. In this lecture, Prof. Andy McNally will show two distinct approaches, using phosphorus and ring-opened intermediates, that enable selective functionalization of these heterocycles into a range of valuable derivatives. A range of C–C and C–Heteroatom bond formations are viable, and the chemistry functions on structures typically encountered in drug discovery programs. Prof. McNally's lab has also performed mechanistic and computational studies of the regioselectivity of these reactions and the phosphorus ligand-coupling processes involved.
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Pharmaron转发了
Discover Pharmaron's Advanced AAV Gene Therapy Platform! At Pharmaron, we have developed a robust platform process for creating AAV gene therapies, equipped with a highly adaptive toolbox to manage various AAV products and serotypes. Our innovative toolbox allows us to rapidly assess a product’s compatibility with our platform and finely tune multiple parameters for optimal results. Learn more by downloading our poster: Utilising HTPD and DoE to Optimise the Pharmaron Gene Therapy Platform: https://lnkd.in/e9w2Xj7c #GeneTherapy #AAV #Biotechnology #Pharmaron #HTPD #DoE #Innovation
Utilising HTPD and DoE to Optimise the Pharmaron Gene Therapy Platform
https://www.pharmaron.com