Fifty Years

The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if entrepreneurship is for you? Whether you’re validating an idea or ready to build — 5050 is for you. You’ll learn what it takes to become a great founder, how to choose the right problem, technology, and market, and how to build a deep tech startup. “It’s a cheat code for starting a deep tech startup.” – Eric McShane, 5050 alum. • Eric McShane and Evan Gardner spun out of Stanford and co-founded Electroflow Technologies to tackle the lithium shortage. They’ve scaled their tech by 200x in 6 months. • Mark Budde joined 5050 as a postdoc at Caltech. Two years later, Plasmidsaurus enables scientists across all 50 states and most European countries to go much faster. • Niccolo Cymbalist joined as a Tesla engineer. Three months later, he co-founded Clippership and is building autonomous sailboats to decarbonize maritime shipping. • Chi Zhang and Tay Shin joined as postdocs at MIT. Within weeks, they spun out and are now working to enable in vivo cell reprogramming. At Fifty Years, we’ve built deep tech companies ourselves. We’ve backed over 100 deep tech startups from the earliest stages and helped them raise over 4.6 billion dollars. We distilled everything we know about deep tech startups into 5050: a free program to help world-class scientists and engineers start indispensable companies. Phase I: Explore We’ll help you answer: How do I turn my breakthrough science into a business? What do I need to make a startup idea work? Am I ready to be a founder?  You’ll learn if entrepreneurship is right for you, identify the idea to build, and pivot quickly if necessary. We’ll guide you through the early days of building in deep tech. At the end of Explore, those ready to build a startup will be invited to the next phase, Build. Phase II: Build You’ll join a cohort of fast-moving founders who will challenge you to ramp up. We’ll coach you to level up into a great founder and guide you through the early days of building in deep tech. Build will help you de-risk your technology, hit key milestones, raise a first round, and reach takeoff speed fast. Helping great scientists and engineers become great entrepreneurs is our jam. Apply / nominate! fiftyyears.com/5050

The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if entrepreneurship is for you? Whether you’re validating an idea or ready to build — 5050 is for you. You’ll learn what it takes to become a great founder, how to choose the right problem, technology, and market, and how to build a deep tech startup. “It’s a cheat code for starting a deep tech startup.” – Eric McShane, 5050 alum. • Eric McShane and Evan Gardner spun out of Stanford and co-founded Electroflow Technologies to tackle the lithium shortage. They’ve scaled their tech by 200x in 6 months. • Mark Budde joined 5050 as a postdoc at Caltech. Two years later, Plasmidsaurus enables scientists across all 50 states and most European countries to go much faster. • Niccolo Cymbalist joined as a Tesla engineer. Three months later, he co-founded Clippership and is building autonomous sailboats to decarbonize maritime shipping. • Chi Zhang and Tay Shin joined as postdocs at MIT. Within weeks, they spun out and are now working to enable in vivo cell reprogramming. At Fifty Years, we’ve built deep tech companies ourselves. We’ve backed over 100 deep tech startups from the earliest stages and helped them raise over 4.6 billion dollars. We distilled everything we know about deep tech startups into 5050: a free program to help world-class scientists and engineers start indispensable companies. Phase I: Explore We’ll help you answer: How do I turn my breakthrough science into a business? What do I need to make a startup idea work? Am I ready to be a founder?  You’ll learn if entrepreneurship is right for you, identify the idea to build, and pivot quickly if necessary. We’ll guide you through the early days of building in deep tech. At the end of Explore, those ready to build a startup will be invited to the next phase, Build. Phase II: Build You’ll join a cohort of fast-moving founders who will challenge you to ramp up. We’ll coach you to level up into a great founder and guide you through the early days of building in deep tech. Build will help you de-risk your technology, hit key milestones, raise a first round, and reach takeoff speed fast. Helping great scientists and engineers become great entrepreneurs is our jam. Apply / nominate! fiftyyears.com/5050

The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if entrepreneurship is for you? Whether you’re validating an idea or ready to build — 5050 is for you. You’ll learn what it takes to become a great founder, how to choose the right problem, technology, and market, and how to build a deep tech startup. “It’s a cheat code for starting a deep tech startup.” – Eric McShane, 5050 alum. • Eric McShane and Evan Gardner spun out of Stanford and co-founded Electroflow Technologies to tackle the lithium shortage. They’ve scaled their tech by 200x in 6 months. • Mark Budde joined 5050 as a postdoc at Caltech. Two years later, Plasmidsaurus enables scientists across all 50 states and most European countries to go much faster. • Niccolo Cymbalist joined as a Tesla engineer. Three months later, he co-founded Clippership and is building autonomous sailboats to decarbonize maritime shipping. • Chi Zhang and Tay Shin joined as postdocs at MIT. Within weeks, they spun out and are now working to enable in vivo cell reprogramming. At Fifty Years, we’ve built deep tech companies ourselves. We’ve backed over 100 deep tech startups from the earliest stages and helped them raise over 4.6 billion dollars. We distilled everything we know about deep tech startups into 5050: a free program to help world-class scientists and engineers start indispensable companies. Phase I: Explore We’ll help you answer: How do I turn my breakthrough science into a business? What do I need to make a startup idea work? Am I ready to be a founder?  You’ll learn if entrepreneurship is right for you, identify the idea to build, and pivot quickly if necessary. We’ll guide you through the early days of building in deep tech. At the end of Explore, those ready to build a startup will be invited to the next phase, Build. Phase II: Build You’ll join a cohort of fast-moving founders who will challenge you to ramp up. We’ll coach you to level up into a great founder and guide you through the early days of building in deep tech. Build will help you de-risk your technology, hit key milestones, raise a first round, and reach takeoff speed fast. Helping great scientists and engineers become great entrepreneurs is our jam. Apply / nominate! fiftyyears.com/5050

The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if entrepreneurship is for you? Whether you’re validating an idea or ready to build — 5050 is for you. You’ll learn what it takes to become a great founder, how to choose the right problem, technology, and market, and how to build a deep tech startup. “It’s a cheat code for starting a deep tech startup.” – Eric McShane, 5050 alum. • Eric McShane and Evan Gardner spun out of Stanford and co-founded Electroflow Technologies to tackle the lithium shortage. They’ve scaled their tech by 200x in 6 months. • Mark Budde joined 5050 as a postdoc at Caltech. Two years later, Plasmidsaurus enables scientists across all 50 states and most European countries to go much faster. • Niccolo Cymbalist joined as a Tesla engineer. Three months later, he co-founded Clippership and is building autonomous sailboats to decarbonize maritime shipping. • Chi Zhang and Tay Shin joined as postdocs at MIT. Within weeks, they spun out and are now working to enable in vivo cell reprogramming. At Fifty Years, we’ve built deep tech companies ourselves. We’ve backed over 100 deep tech startups from the earliest stages and helped them raise over 4.6 billion dollars. We distilled everything we know about deep tech startups into 5050: a free program to help world-class scientists and engineers start indispensable companies. Phase I: Explore We’ll help you answer: How do I turn my breakthrough science into a business? What do I need to make a startup idea work? Am I ready to be a founder?  You’ll learn if entrepreneurship is right for you, identify the idea to build, and pivot quickly if necessary. We’ll guide you through the early days of building in deep tech. At the end of Explore, those ready to build a startup will be invited to the next phase, Build. Phase II: Build You’ll join a cohort of fast-moving founders who will challenge you to ramp up. We’ll coach you to level up into a great founder and guide you through the early days of building in deep tech. Build will help you de-risk your technology, hit key milestones, raise a first round, and reach takeoff speed fast. Helping great scientists and engineers become great entrepreneurs is our jam. Apply / nominate! fiftyyears.com/5050

Ginkgo Bioworks is in the midst of a 25% layoff (around 300 employees) - I found out today that I can continue being employed there It’s definitely bittersweet - I didn’t want to be looking for a new job - particularly since the biotech job market right now is terrible - too many companies laying off, too few starting or growing But many super-talented, interesting people I enjoyed working with are now looking for their next job. I’m still figuring out who is out immediately, who is on a deferred layoff and who is staying You could build several excellent small biotech companies from who has been cast off - all levels of personnel were hit and every specialty - IT, Data Science, Facilities, Business Development, Software, Computational Biology, Microbiology, Molecular Biology, Mammalian Cell Culture, LC/MS, etc Most people Boston-based, a number in CA and many others working remotely So if you know of opportunities out there, I’d be very happy to pass them on - there’s an Slack community set up for current and former Ginkgo employees that is useful for distributing job leads