Our focus is immunology, because we believe that no other biomedical discipline has greater implications for human health than immunology. By unraveling the complexities of the immune system, LJI researchers are directly tackling an extraordinarily diverse array of diseases, which together account for more than two-thirds of all deaths in the U.S. each year. Such diseases include type 1 diabetes, cancer, COVID-19, rheumatoid arthritis, multiple sclerosis, asthma, allergies, influenza, dengue fever, and many other illnesses. La Jolla Institute is home to four research centers that focus the efforts of collaborative groups of researchers on defined areas of inquiry, to accelerate progress toward the development of new treatments and vaccines to prevent and cure autoimmune conditions, cancer, and infectious disease, and to uncover the largely unexplored sex-specific variables in immune responses. LJI is host to three national databases that give biomedical researchers free access to the world’s largest collection of epitopes and related scientific data and provide insights into how genes act within the immune system to set it in motion. Life without Disease is a pursuit that requires a continually expanding understanding of the immune system, and the ability to translate knowledge and discoveries developed in scientific research into technologies that improve life and health. Learn more at https://www.lji.org
La Jolla Institute for Immunology
Research Services
La Jolla, CA 10,747 followers
Dedicated to understanding the intricacies and power of the immune system; striving toward a Life Without Disease ®.
About us
"Sometimes in science there are so many people trying to answer the same question that it's good to stray off in another direction," Mitchell Kronenberg, Ph.D., LJI Professor. "Taking the road less traveled can bring its voyagers to unexpected - and even groundbreaking - new territory." The La Jolla Institute The La Jolla Institute for Immunology is a non-profit medical research institute dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases. What is immunology? Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune response. The immune response is the defense system of the body carried out by white blood cells against microbial threats such as a virus infection. Since immunology has an effect on every organ system in our body, there is no biomedical discipline that has greater implications for improving human health. Where is LJI? The La Jolla Institute is located in the University of California San Diego's Science Research Park in a world-class facility covering 145,000 square feet. Our space provides an open laboratory setting that encourages La Jolla Institute for Immunology's highly collaborative research environment.
- Website
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https://www.lji.org
External link for La Jolla Institute for Immunology
- Industry
- Research Services
- Company size
- 201-500 employees
- Headquarters
- La Jolla, CA
- Type
- Nonprofit
- Founded
- 1988
Locations
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Primary
9420 Athena Circle
La Jolla, CA 92037, US
Employees at La Jolla Institute for Immunology
Updates
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Exciting new work reveals—in unprecedented detail—how a powerful antibody can neutralize measles virus before it fuses with host cells. When measles virus meets a human cell, the viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane. Once the fusion process is complete, the host cell is a goner. It belongs to the virus now. Scientists in the LJI Center for Vaccine Innovation are working to develop new measles vaccines and therapeutics that stop this fusion process. Erica Ollmann Saphire , Dawid Zyla , Matteo Porotto https://lnkd.in/gfUm5RzH #Virology #Antibodies #VaccineResearch #InfectiousDisease #Measles #StructuralBiology #CryoEM
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We are thrilled to welcome a new class of summer interns to the 2024 LJIdea Internship Program! Thank you to the supporters, mentors, and scientists who came to this morning's White Coat Ceremony at LJI! Let the research begin! #SanDiego #STEM #TeachSTEM #Science #Immunology #internship
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A new LJI study, published recently in Nature Immunology, is the first to show a link between “stem-like” T cells and ulcerative colitis in human patients. “We’ve found a population of T cells that may be important in disease—and may contribute to relapse in patients with ulcerative colitis,” says LJI William K. Bowes Distinguished Professor Pandurangan "Vijay" Vijayanand, M.D., Ph.D., who co-led the study with LJI Professor Mitchell Kronenberg, Ph.D. The researchers hope to one day target this T cell population via drug therapy. “These cells may be a very important target for treating ulcerative colitis and perhaps other autoimmune diseases,” says Kronenberg. https://lnkd.in/gmjWUnQ3 #tcell #ulcerativecolitis #autoimmunedisease #research #immunology
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Congratulations to LJI Instructor Sydney Ramirez, MD, Ph.D., who has won the prestigious Burroughs Wellcome Fund Career Award for Medical Scientists in recognition of her critical research into how the human immune system and cells in the upper airway respond to SARS-CoV-2, the virus that causes COVID-19. "Very few people—and very few clinician scientists—get this award," says LJI Professor and Chief Scientific Officer Shane Crotty, Ph.D. "This award really speaks to how important Sydney's research has been and the promise for her career going forward." The award goes to outstanding early-career researchers who have demonstrated exceptional promise in the field of medical science, and comes with substantial research funding to support innovative research and advance human health. Congrats! 🎉 https://lnkd.in/gG8td86T
Sydney Ramirez receives prestigious Burroughs Wellcome Fund Career Award
https://www.lji.org
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Congratulations to LJI Postdoc Isaac López-Moyado, Ph.D., who has been awarded the Fred Hutch 2024 Dr. Eddie Méndez Scholar Award, which recognizes exceptional postdoctoral researchers from historically underrepresented groups in science! https://bit.ly/3Vxex8g
Congratulations to the eight recipients of the 2024 Dr. Eddie Méndez Scholar Award! This award recognizes outstanding early-career scientists from underrepresented backgrounds who are studying cancer, infectious diseases and basic sciences. Learn more: https://lnkd.in/gQgArx83
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Exciting news: In recognition of her exceptional research track record, LJI Research Assistant Professor Daniela Weiskopf, Ph.D., has been appointed to a tenure-track Assistant Professor position 🎉. Weiskopf’s laboratory studies protective and maladapted immune responses to emerging infectious diseases. “LJI has been my scientific home for many years and the place where my research could flourish,” says Weiskopf. “I feel truly honored to be joining the ranks of tenure-track faculty, and my commitment to the Institute is just as strong as the commitment the Institute has shown by promoting me.” Congrats!!! Read more about Dr. Weiskopf's impactful work here: https://lnkd.in/gTNy5k8h #Tcells #AdaptiveImmunity #VaccineResearch #Immunology #SanDiego #COVID19 #Dengue #Virology #tenure #researcher
Daniela Weiskopf appointed LJI Assistant Professor
https://www.lji.org
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“So often, stories about disease are focused on the negative,” says LJI Creative Producer Matthew Ellenbogen. “But [Kat's] story is really a story of modern medicine and basic research leading to treatments for people—that let them live the life that they want to live.” Filmmaker Matt Ellenbogen captures a unique side of science—learn how an LJI documentary made it to the Golden State Film Festival and Hollywood's historic Chinese Theater. https://lnkd.in/g5DpucsQ #SanDiego #SciComm #Filmmaking
Filmmaker Matthew Ellenbogen captures a unique side of science
https://www.lji.org
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LJI scientists are developing a new method to match genes to their molecular ‘switches’, helping to hunt down solid tumors and better diagnose disease. “This research is about bringing a three-dimensional perspective to studying DNA modifications and their function in our genome,” says LJI Associate Professor Ferhat Ay, Ph.D., who co-led the study with LJI Professor Anjana Rao, Ph.D. #genes #cancer #tumor #genomics #computationalbiology Edahí González Avalos https://lnkd.in/dvet5eK4
LJI scientists develop new method to match genes to their molecular ‘switches’
https://www.lji.org
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New research suggests people who received COVID-19 vaccines and then experienced “breakthrough” infections are especially well armed against future SARS-CoV-2 infections. By analyzing blood samples from study volunteers, LJI researchers discovered that people who experienced symptomatic breakthrough infections develop T cells that are better at recognizing and targeting SARS-CoV-2, including the Omicron and Delta variants. The researchers describe this increased protection as an “immunity wall.” Alessandro Sette , Shane Crotty , Alba Grifoni , Alison Tarke , Parham Rad #COVID #Tcell #Bcell #immunity https://lnkd.in/dg7Sc-Wp
How COVID-19 ‘breakthrough’ infections alter your immune cells
https://www.lji.org