Pharmacology Research Associate/Senior Research Associate

Position Summary:

Seeking a Senior Research Associate for our Pharmacology and Toxicology group. This individual will play a key role in the development and execution of preclinical models to understand the efficacy and PK/PD relationships of our small molecule agents under development for the treatment of cancer.

What you’ll do:

• Play a key role in evaluating mechanistic hypotheses for drug responses using samples generated from in-vivo studies, utilizing diverse molecular biology techniques to assess gene modulation and interrogate pathways of interest.

• Lead the development and implementation of ex-vivo assays for screening new potential therapeutics in vivo.

• Contribute to method development for new ex-vivo assays, experimental protocols, and related readouts for specific project needs.

• Collaborate with research teams on relevant ex vivo assays (Western Blot, qPCR, MSD, IHC, Flow Cytometry, etc.)

• Design and manage research experiments, and analyze and interpret scientific data under general supervision

• Present data and report on project status at team, intra- and inter-departmental research meetings

• Support general laboratory functions and organization as needed.

• Document all laboratory activities, protocols, analysis methods and the collection of data.

Requirements:

• BA/BS or MS with 1+ years’ (Research Associate) or 3+ years’ (Senior Research Associate) laboratory experience in cancer biology, biochemistry, cell biology, immunology or related field.

• Practical laboratory experience handling and processing of animal tissues for DNA, RNA, and protein extraction.

• Experience in mammalian tissue culture and ex vivo assays such as western blot, ELISA, gene expression analysis (qRT-PCR), flow cytometry, MSD, IF, and IHC.

• Experience in assay development, optimization and troubleshooting is a plus.

• Ability to effectively design, plan, execute, and analyze experiments under general supervision.

• Efficient time management and the ability to adapt to shifting priorities and timelines.

• Strong interpersonal skills and effective communication with cross function team members