Senior Research Associate, Biology

Summary

As an emerging, global biotech with locations in Boston, Massachusetts, Basel, Switzerland, London, England and Oslo, Norway, we take advantage of diverse scientific depth and insights that makes ARTBIO a unique place to work. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration.

This opportunity is for a person who strives to innovate, is never satisfied with routines, and has a strong heart for ARTBIO’s mission. A self-starter and innovator, you will be part of a cross-function team to spearhead key programs from our internal and partnered Discovery portfolio as well as support the build of the Early Discovery Biology disciplines at ARTBIO-Cambridge.

Responsibilities

• Perform cell-based studies to support the identification and validation of novel targets as well as the advancement of drug discovery projects from hit discovery through development candidate selection
• Demonstrate proficiency in mammalian cell line engineering using CRISPR, RNAi, and lentivi ral stable cell line generation, comfortable working with numerous cell lines simultaneously
• Execute specimen preparation, staining, sample acquisition, and analysis of flow cytometric data
• Interrogate cell signaling pathways using western blotting, qPCR, RNAseq
• Independently design and execute cell-based experiments and share results in a variety of settings
• Analyze experimental results, brainstorm, and troubleshoot findings thoughtfully and proactively
• Work seamlessly with multiple drug discovery teams to provide technical support at all stages of the project
• Multi-task and collaborate effectively with other scientists and research associates to accomplish goals on tight timelines.
• Ability to navigate in a start-up environment and adapt to the ‘unknown’
• Maintain compliance with lab documentation to enable collaboration among multinational project teams
  
  
  

Qualifications

• BA/MA in Biology or related discipline, with 3-5+ years of industrial experience, or equivalent
• Background in cancer biology with experience and demonstrated success using cell biology techniques to enable discovery biology
• Strong technical skills in mammalian cell culture are required; proficiency and independence with core techniques such as Western blotting, CRISPR, flow cytometry, and phenotypic assays are also essential
• Experience in the development, optimization, and execution of quantitative cellular assays to support small molecule drug discovery from hit confirmation through lead optimization
• Previous experience with plate-based complementation assays is preferred
• Excellent organizational, communication, multi-tasking, and collaboration skills
• Outstanding problem-solver, driven by innovative approaches, and comfortable working in a fast-paced startup environment
• Focus on the “we” rather than the “me”
• Driven by patients, passionate about our company culture, inclusive and respectful of all colleagues
  
  
  

About Us

ARTBIO is a clinical-stage radiopharmaceutical company redefining cancer care by creating a new class of alpha radioligand therapies (ARTs). The unique ARTBIO approach selects the optimal alpha-precursor isotope (212Pb) and tumor-specific targets to create therapeutics with the potential for highest efficacy and safety. The company's AlphaDirect™ technology, a first-of-its-kind 212Pb isolation method, enables a distributed manufacturing approach for the reliable production and delivery of ARTs. ARTBIO is advancing multiple pipeline programs with lead program AB001 currently in first in human trials. ARTBIO is shaped by a long-standing scientific legacy with nearly a century of pioneering work in radiation therapy conducted at the University of Oslo and Norway’s Radium Hospital. For more information, visit www.artbio.com, and follow us on LinkedIn and Twitter.

As an emerging, global biotech with locations in Boston, Massachusetts, Basel, Switzerland, London, England and Oslo, Norway, we take advantage of diverse scientific depth and insights which makes ARTBIO a unique place to work. We are driven by a desire to do better for cancer patients, lowering the burden of toleration and safety while at the same time raising the bar on clinical efficacy and duration.

EEO Statement

ARTBIO is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.